役職名		小児科講師
所　属		小児科学講座
氏　名		吉田　真
専門分野		血液・腫瘍学
出身大学（期）		東海大学医学部（9期）
出身高校		函館中部
国内・国外留学など		東京大学医科学研究所癌病態研究部
所属学会・ 専門医		日本小児科学会（専門医）、日本血液学会（専門医･指導医）、日本癌化学療法学会（暫定指導医2007から10年間）、日本小児血液学会、日本臨床血液学会、日本小児がん学会、日本造血細胞移植学会、日本検査血液学会
専門詳細		小児血液学、小児悪性腫瘍学、造血幹細胞移植
研究テーマ・内容		造血幹細胞の生体外増幅 採取量に限度のある臍帯血などの造血幹細胞を増幅することで臨床に直結した活用拡大を図る。
一　言		血液腫瘍疾患の子供たちの力になれるよう誠心誠意頑張っています。また小児血液腫瘍学に少しでも貢献できるよう頑張っています。
英文業績 （1996〜2007）		Tajima S, Tsuji K, Ebihara Y, Sui X, Tanaka R, Muraoka K, Yoshida M, Yamada K, Yasukawa K, Taga T, Kishimoto T, Nakahata T.: Analysis of interleukin 6 receptor and gp130 expressions and proliferative capability of human CD34+ cells. J Exp Med. 1996 Oct 1;184(4):1357-64. Yoshida M, Tsuji K, Ebihara Y, Muraoka K, Tanaka R, Miyazaki H, Nakahata T. : Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum-free culture. Br J Haematol. 1997 Aug;98(2):254-64. Muraoka K, Tsuji K, Yoshida M, Ebihara Y, Yamada K, Sui X, Tanaka R, Nakahata T. : Thrombopoietin-independent effect of interferon-gamma on the proliferation of human megakaryocyte progenitors. Br J Haematol. 1997 Aug;98(2):265-73. Kobayashi R, Kumon K, Watanabe N, Iguchi A, Cho Y, Yoshida M, Arioka H, Naito H, Shikano T, Ishikawa Y. : Antithymocyte globulin as conditioning regimen for bone marrow transplantation Rinsho Ketsueki. 1997 Nov;38(11):1183-8. Ebihara Y, Tsuji K, Lyman SD, Sui X, Yoshida M, Muraoka K, Yamada K, Tanaka R, Nakahata T. : Synergistic action of Flt3 and gp130 signalings in human hematopoiesis. Blood. 1997 Dec 1;90(11):4363-8. Kobayashi R, Watanabe N, Iguchi A, Cho Y, Yoshida M, Arioka H, Naito H, Shikano T, Ishikawa Y. : Electroencephalogram abnormality and high-dose busulfan in conditioning regimens for stem cell transplantation. Bone Marrow Transplant. 1998 Feb;21(3):217-20. Sui X, Tsuji K, Ebihara Y, Tanaka R, Muraoka K, Yoshida M, Yamada K, Yasukawa K, Taga T, Kishimoto T, Nakahata T. : Soluble interleukin-6 (IL-6) receptor with IL-6 stimulates megakaryopoiesis from human CD34(+) cells through glycoprotein (gp)130 signaling. Blood. 1999 Apr 15;93(8):2525-32. Kobayashi R, Kaneda M, Watanabe N, Iguchi A, Cho Y, Yoshida M, Arioka H, Naito H, Shikano T, Ishikawa Y. : Adverse effects of anti-thymocyte globulin/anti-lymphocyte globulin therapy Rinsho Ketsueki. 1999 Jul;40(7):531-5 Iguchi A, Kobayashi R, Yoshida M, Kaneda M, Watanabe N, Cho Y, Arioka H, Naito H, Shikano T, Ishikawa Y. : Neurological complications after stem cell transplantation in childhood. Bone Marrow Transplant. 1999 Sep;24(6):647-52. Kobayashi R, Arioka H, Yoshida M, Cho Y, Iguchi A, Kaneda M, Shikano T. : Prolonged bone marrow failure with monosomy 7 after engraftment failure following bone marrow transplantation. Int J Hematol. 2001 Feb;73(2):258-61. Oka M, Terae S, Kobayashi R, Kudoh K, Chu BC, Kaneko K, Yoshida M, Kaneda M, Suzuki Y, Miyasaka K. : Diffusion-weighted MR findings in a reversible case of acute Wernicke encephalopathy. Acta Neurol Scand. 2001 Sep;104(3):178-81. Ueda T, Yoshida M, Yoshino H, Kobayashi K, Kawahata M, Ebihara Y, Ito M, Asano S, Nakahata T, Tsuji K. : Hematopoietic capability of CD34+ cord blood cells: a comparison with CD34+ adult bone marrow cells. Int J Hematol. 2001 Jun;73(4):457-62. Iguchi A, Kobayashi R, Yoshida M, Kobayashi K, Matsuo K, Kitajima I, Maruyama : Vascular endothelial growth factor (VEGF) is one of the cytokines causative and predictive of hepatic veno-occlusive disease (VOD) in stem cell transplantation. Bone Marrow Transplant. 2001 Jun;27(11):1173-80. Yumura-Yagi K, Hara J, Horibe K, Tawa A, Komada Y, Oda M, Nishimura S, Yoshida M, Kudo T, Ueda K; Japan Association of Childhood Leukemia Study. : Outcome after relapse in childhood acute lymphoblastic leukemia. Int J Hematol. 2002 Jul;76(1):61-8. Oka M, Terae S, Kobayashi R, Sawamura Y, Kudoh K, Tha KK, Yoshida M, Kaneda M, Suzuki Y, Miyasaka K. : MRI in methotrexate-related leukoencephalopathy: Disseminated necrotising leukoencephalopathy in comparison with mild leukoencephalopathy. Neuroradiology. 2003 Jul;45(7):493-7. Epub 2003 May 22. Kobayashi R, Iguchi A, Nakajima M, Sato T, Yoshida M, Kaneda M, Suzuki Y, Mino E, Kuroki F, Kobayashi K. : Hyponatremia and syndrome of inappropriate antidiuretic hormone secretion complicating stem cell transplantation. Bone Marrow Transplant. 2004 Sep 27 [Epub ahead of print] Mino E, Kobayashi R, Yoshida M, Suzuki Y, Yamada M, Kobayashi K : Umbilical cord blood stem cell transplantation from unrelated HLA-matched donor in an infant with severe congenital neutropenia. Bone Marrow Transplant. 2004 May;33(9):969-71. Makita Y, Narumi Y, Yoshida M, Niihori T, Kure S, Fujieda K, Matsubara Y, Aoki Y. : Leukemia in cardio-facio-cutaneous (CFC) syndrome: a patient with a germline mutation in BRAF proto-oncogene　J Pediatr. Hematol/Onco 2007 Umeda K, Yoshida M, Suzuki N, Endo M, Sato A, Hori H, Isogai M, Matsumoto K, Hara JI, Hasegawa D, Hashii Y, Chayama K, Miyaji R, Nishimura S, Tanizawa A, Uami I, Horibe K, Wakazono Y, Yagi K. : Complications in the central nervous system during chemotherapy for childhood acute lymphoblastic leukemia: JACLS ALL-02 study Rinsho Ketsueki. 2007 Mar;48(3):204-11.